In 1975, scientists engaged in an invitation-only conference meant to encourage self-regulation of a new genetic engineering technology that many thought posed significant threats to the living world: recombinant DNA. This meeting met in Monterey, CA at a resort called Asilomar, a name that would ring on for decades as a purported model for scientists wrestling with the social implications of the breakthrough technologies they develop.
In the past few years, a new suite of synthetic biology tools known as “gene editors” (ZFNs, TALENs, and CRISPR/Cas9) has made possible the widespread and unforeseen consequences of genetically engineering flora, fauna, and ourselves, and “Asilomar” once again became a rallying cry. Yet many[Nature Editorial Board] prominent[Ben Hurlbut] voices[Sheila Jasanoff, Kris Saha & Hurlbut] have pushed back on this metaphorical monolith, noting the 1975 meeting’s extremely insular nature, its structural bias wherein defining risk was left to scientists alone, and its rapidly diminishing usefulness as a model in the modern global context of science and human society.
Cognizant of these critiques—yet tied to the “mythic” Asilomar as one of its principal organizers—David Baltimore, chair of the organizing committee for the International Summit on Gene Editing, opened the meeting (somewhat less insular, still mostly invitation-based) with the following remarks:
… a lot has changed since 1975. Science has become an increasingly global enterprise … The public also has become more engaged in debates about science and scientific progress, and the new modes of rapid communication have provided novel platforms for these discussions. At Asilomar, the press participated with the understanding that nothing would be written about what was said until the meeting is concluded.
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