(Medscape) – In addition to age, ovarian reserve can be tested by multiple laboratory markers. Commonly, estradiol and follicle-stimulating hormone levels are measured at the beginning of the cycle, but early-cycle estradiol alone, inhibin B, and anti-Müllerian hormone (AMH) can also be used. There are dynamic tests that evaluate hormonal changes in response to clomiphene, gonadotropin-releasing hormone agonist, or gonadotropin. Ultrasound evaluation of the antral follicle count, ovarian volume, or Doppler indices can also be used. Finally, the combination of these tests may provide an even better estimate of the size of the follicle pool.
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