Lung organoids have been produced from human pluripotent stem (iPS) cells that contain various components of lung tissue, and even airways and alveolar structures (see HERE). Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D) would allow deeper insight into human development, as well as the development of innovative strategies for disease modelling, drug discovery and regenerative medicine. Lung organoids produced resemble those of the second trimester of pregnancy. The authors discuss the potential use of this model to study pulmonary fibrosis in vitro and to model lung diseases.
La entrada Pulmonary organoids produced from human iPS cells in three dimensions (3D) aparece primero en Bioethics Observatory.
Source: Bioethics Observatory.
This article was originally published by the Bioethics Observatory of the Catholic University of Valencia. Up-to-date news and reports from the Bioethics Observatory at the Catholic University of Valencia (Spain), covering a wide range of bioethical issues including stem cell research, abortion, assisted suicide and much more. General interest and specialised topical articles with ethical implications, based on the latest research findings from some of the world's top medical and scientific journals.