February 17, 2017
(Medical Xpress) – The researchers established a method of investigating how Zika alters the production, survival and maturation of brain stem cells using cells donated from three human fetal brains. They focused on the impact of the Asian lineage Zika virus that was involved in the first outbreak in North America in late 2015. “We discovered that the Asian lineage Zika virus halted the proliferation of brain stem cells and hindered their ability to develop into brain nerve cells,” said Ping Wu, senior author on the study and UTMB professor in the Department of Neuroscience & Cell Biology.
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