October 27, 2016
(JAMA) – As part of his 1984 doctoral thesis, Church developed and described the first direct DNA sequencing method that became the precursor to modern-day next-generation sequencing approaches. Church was involved in launching the Human Genome Project and received 1 of its first grants. In 2013, his laboratory was 1 of 2 that described human genome editing using CRISPR-Cas9. More recently, he’s been working on genome-scale engineering of Escherichia coli—proof-of-concept for HGP-write. As the project moves forward, Church said his laboratory will develop and test innovations like generating transplantable organs from altered stem cells.
The views, opinions and positions expressed by these authors and blogs are theirs and do not necessarily represent that of the Bioethics Research Library and Kennedy Institute of Ethics or Georgetown University.