Female infertility: a new discovery. Approximately 15% of couples suffer from infertility. This may due to either a male or female factor. A new step has now been taken in the search for the causes of it, with the discovery of alterations in the gene that expresses tubulin, which when altered, interrupts oocyte maturation. The authors said, “We identified seven mutations in the primate-specific gene TUBB8that were responsible for oocyte meiosis I arrest in 7 of the 24 families. These mutations have dominant-negative effects that disrupt microtubule behavior and oocyte meiotic spindle assembly and maturation, causing female infertility” (New England Journal of Medicine 374; 223-232, 2016).
La entrada Female infertility. Discovery of alterations in a gene which when altered causes it aparece primero en Observatorio de Bioética, UCV.
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