Bioethics News

Female infertility. Alterations discovered in a gene that could affect it

Female infertility: a new discovery. Approximately 15% of couples suffer from infertility. This may due to either a male or female factor. The study Resut says, “We identified seven mutations in the primate-specific gene TUBB8that were responsible for oocyte meiosis I arrest in 7 of the 24 families. TUBB8 expression is unique to oocytes and the early embryo, in which this gene accounts for almost all the expressed β-tubulin”. A new step has now been taken in the search for the causes of female infertility, with the discovery of these alterations in the gene that expresses tubulin, which when altered, interrupts oocyte maturation (Read HERE, New England Journal of Medicine 374; 223-232, 2016).

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