June 21, 2016
(Medscape) – The authors studied the frequency of birth defects among liveborn infants in three states over a 10-year period and evaluated the impact of ART use. Various linked databases were used for data collection. The prevalence of chromosomal (chromosomes 13, 18, and 21) and nonchromosomal birth defects of specific organ systems were compared. Maternal age, race, education, parity, history of diabetes, hypertension, smoking status, plurality of pregnancy, infant sex, birth weight, and gestational age at delivery were adjusted for during the analysis. Subgroup analysis was carried out for types of ART procedures.
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